Cardiology Associates of Fairfield County, P.C.
Clinical Research Group
Active Trials
The following trials are currently ongoing and in long-term follow-up:
Patients with Atrial Fibrillation
The Gloria Registry
Brief Title: GLORIA-AF Registry Program
Official Title: GLORIA - AF: Global Registry on Long-Term Oral Anti-thrombotic Treatment In Patients With Atrial Fibrillation (Phase II/III)
NCT Government ID: NCT01468701
Inclusion Criteria:
Patients newly diagnosed with non-valvular atrial fibrillation (NVAF) at risk for stroke.
Exclusion criteria:
Presence of any mechanical heart valve, or valve disease that is expected to require valve replacement intervention
Patients who have received more than 60 days of vitamin K antagonist (VKA) treatment in their lifetime
AF with a generally reversible cause;
Patients with a medical condition other than atrial fibrillation for which chronic use of an oral anticoagulant (for example, a VKA) is indicated
What is the purpose of this study?
In this part of the Registry Program patients with non-valvular atrial fibrillation (AF) at risk for stroke are enrolled to characterize the target population and to collect real world data on important outcome events. The total number of patients enrolled in both protocols is estimated to be 48,000 patients, and all these patients will be included in the data analysis for study 1160.129.
Lead Sponsor: Duke University
Collaborator: National Heart, Lung, and Blood Institute (NHLBI)
Technical Information: http://clinicaltrials.gov/ct2/show/NCT00786474
Condition Name: Arterial Thromboembolic Events, Atrial Fibrillation
ARTESiA
Apixaban vs. Aspirin in Sub-Clinical Atrial Fibrillation - Stamford office only.
Patients with Heart Failure
Galactic
Omecamtiv Mecarbil vs. placebo in patients with Heart Failure with Reduced Ejection Fraction.
CHAMP-HF Registry
Heart Failure Registry
DELIVER
Dapagliflozin vs. placebo in patients with Heart Failure with Preserved Ejection Fraction - Stamford office only.
DETERMINE
Dapagliflozin vs. placebo in patients with Heart Failure with Reduced Ejection Fraction - Stamford office only.
Omecamtiv Mecarbil Immunoassay
Immunoassay sample collection for Omecamtiv Mecarbil exposed and de novo subjects.
Patients Needing a Pacemaker or Defibrillator
MultiPoint Pacing Post Market Study
For anyone getting an MPP device.
SCORE Registry
Long-term St. Jude Medical/Abbott device registry.
MORE-CRT MPP
Patients getting a BiV or BiV upgrade who are non-responders to traditional CRT programming.
Patients with High Cholesterol
GOULD Registry
Lipid Management Registry
CLEAR
Bempedoic Acid vs. placebo in statin-intolerant patients - Stamford office only.
ORION-4
Inclisiran vs. placebo in patients with Coronary or Peripheral Artery Disease and a prior qualifying event - Stamford and Norwalk offices only.
Vesalius-CV
Repatha vs. placebo in patients with Coronary or Peripheral Artery Disease or risk factors without a prior event.
Patients with Hypertension
Radiance-HTN (Renal Denervation)
Renal Denervation outpatient procedure at Stamford Hospital for patients on 3+ hypertension medications. Follow-ups in Stamford office
Radiance II (Renal Denervation)
Renal Denervation outpatient procedure at Stamford Hospital for patients on 0-2 hypertension medications. Follow-ups in Stamford office
Patients Needing a Cardiac Stent
Xience 28
DAPT for 1 month post PCI in high bleed risk patients.
value. quality care. convenience.